A new study reveals why some pancreatic and colorectal tumors resist targeted anti-Wnt drugs and suggests how to overcome it, offering new hope to patients with fully treatment-resistant cancers.
Are we missing the forest for the trees? More than timber grows in forests -- including products worth many tens of billions of dollars. Because these goods go unrecorded in official trade statistics, their economic value escapes our attention. As a result, clear opportunities to combat poverty are being missed, according to an economist.
Optimizing electrochemical reactions is essential for the transition to renewable energies. In electrochemical reactions, electric currents and potential differences are used to binding and induce reactions. Electrochemistry is a prerequisite for hydrogen production, and for battery technology, and thus for sustainable chemistry. Although there has been a lot of technological development in this area in recent years, there is still room for improvement and a long way towards large scale industrial applications.
Researchers have found that baby stars discharge plumes of gas, dust, and magnetic flux from their protostellar disk. The protostellar disk that surrounds developing stars are constantly penetrated by magnetic flux, and if too much magnetic flux remained, the resulting object would generate a magnetic field stronger than any observed protostar. These newly discovered discharges of magnetic flux, or 'sneezes' as the researchers describes them, may be a vital step in proper star formation.
Researchers show that ozone levels, such as those found in many places on hot summer days today, destroy the sex pheromones of fruit fly species. As a result, some natural mating boundaries maintained by species-specific pheromones no longer exist. The research team has shown in experiments that flies of different species mate when exposed to ozone and produce hybrid offspring. Since most of these offspring are unable to reproduce, the results could provide another explanation for the global decline of insects.
Meandering ocean currents play an important role in the melting of Antarctic ice shelves, threatening a significant rise in sea levels.
Voids, or empty spaces, exist within matter at all scales, from the astronomical to the microscopic. In a new study, researchers used high-powered microscopy and mathematical theory to unveil nanoscale voids in three dimensions. This advancement is poised to improve the performance of many materials used in the home and in the chemical, energy and medical industries -- particularly in the area of filtration.
Cloud 'engineering' could be more effective for climate cooling than previously thought, because of the increased cloud cover produced, new research shows.
By analyzing the narratives of women who experienced traumatic childbirth and women with non-complicated childbirth, researchers created an AI model that can accurately identify those at risk of childbirth-related PTSD.
So far, biodiversity and agricultural productivity could not be reconciled because the socio-ecological system of agriculture is highly complex, and the interactions between humans and the environment are difficult to capture using conventional methods. A research team now shows a promising way to achieve both goals at the same time. They focus on further developing artificial intelligence in combination with collective human judgement: hybrid intelligence.
A Cystic Fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective in newborns aged four weeks and above, new research suggests.
New hypothesis paper builds on a growing scientific consensus that Parkinson's disease route to the brain starts in either the nose or the gut and proposes that environmental toxicants are the likely source.
A study has found that market forces have provided good food price stability over the past half century, despite extreme weather conditions.
Researchers have developed synthetic platelets that can be used to stop bleeding and enhance healing at the site of an injury. The researchers have demonstrated that the synthetic platelets work well in animal models but have not yet begun clinical trials in humans.
The transition from the esophagus to the stomach is a delicate region from a medical point of view, often associated with pathological disorders leading to cancer. An international research team has now gained new insights into this region. These pave the way for new prevention and treatment options.
A new set of maps that document the movements of ungulates was published today in the fourth volume of the Ungulate Migrations of the Western United States. The maps in this collaborative report series reveal the migration routes and critical ranges used by ungulates, or hooved mammals, in the western U.S., furthering scientists' understanding of the geography of big game migrations.
Storing chemicals in a garage at home may associate with an increased risk of ALS, a study finds. This comes as research has found that exposure to environmental toxins, such as pesticides and volatile organic compounds, are also linked to ALS development. Researchers call the buildup of exposures of the lifetime the ALS exposome.
One of the largest-ever studies on the topic of deprescribing medications shows the potential promise, and pitfalls, of a massive effort to reduce overuse of a common class of heartburn medications known as proton pump inhibitors or PPIs. It also reveals that some of the feared risks from PPIs may be overblown.
Despite their great trust in the on-board autopilot, bridge officers do not believe that autonomous ships will make shipping safer. Moreover, the greater the professional commitment and pride of the bridge officers, the less confidence they have in automation increasing safety at sea.
Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.
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