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Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease

07/06/2024
By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

Mushroom stump waste could be inexpensive, healthy chicken feed supplement

07/06/2024
Feed costs for producing broiler chickens accounts for 60% to 70% of total production costs, and stump waste from the production of button mushrooms comprises nearly 30% of total mushroom weight. Marrying the two has the potential to reduce both cost and waste, especially in Pennsylvania, which is a national leader in the production of broiler chickens and button mushrooms.

Wildfire smoke reached 99% of U.S. lakes in 2019-2021

07/06/2024
Where there's smoke, there's not always fire. Wildfire smoke drifted to nearly every lake in North America for at least one day per year from 2019 to 2021, found a UC Davis study.

Robotic device restores wavelike muscular function involved in processes like digestion, aiding patients with compromised organs

07/06/2024
A team of researchers has developed a wirelessly activated device that mimics the wavelike muscular function in the esophagus and small intestine responsible for transporting food and viscous fluids for digestion.

Study identifies potential pathway to reducing breast cancer brain metastases

07/06/2024
A study has identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain.

How does oxygen depletion disrupt memory formation in the brain?

07/06/2024
When we learn something new, our brain cells (neurons) communicate with each other through electrical and chemical signals. If the same group of neurons communicate together often, the connections between them get stronger. This process helps our brains learn and remember things and is known as long-term potentiation or LTP. Another type of LTP occurs when the brain is deprived of oxygen temporarily -- anoxia-induced long-term potentiationor aLTP. aLTP blocks the former process, thereby impairing learning and memory. Therefore, some scientists think that aLTP might be involved in memory problems seen in conditions like stroke.

Inhibition of epigenetic control enzymes in immune cells as a potential new starting point in cancer immunotherapy

07/06/2024
Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from the so-called dentritic cells of the immune system influences their development and thus improves anti-tumor immunity. This finding could lead to new therapeutic strategies in immunotherapy.

Baby baboon brain anatomy predicts which hand they will use to communicate

07/06/2024
By studying the brain anatomy of newborn baby baboons, a research group was able to predict what hand they would use to communicate after they had been weaned.

Frozen? Let it melt with efficient new de-icer friendly to the environment

07/06/2024
A research team has found a de-icing mixture with high effectiveness and low environmental impact after using machine learning to analyze ice melting mechanisms of aqueous solutions of 21 salts and 16 organic solvents.

Transfer RNAs at the heart of therapeutic resistance

07/06/2024
Scientists have discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies. Inhibition of the VARS enzyme could prevent this therapeutic resistance by resensitizing tumors resistant to these targeted therapies.

What's going on in our brains when we plan?

07/06/2024
An international team of scientists has uncovered neural mechanisms used in planning. Its results suggest that an interplay between the brain's prefrontal cortex and hippocampus allows us to imagine future outcomes in order to guide our decisions.

Perturbations simplify the study of 'super photons'

07/06/2024
Thousands of particles of light can merge into a type of 'super photon' under suitable conditions. Physicists call such a state a photon Bose-Einstein condensate. Researchers have now shown that this exotic quantum state obeys a fundamental theorem of physics. This finding now allows one to measure properties of photon Bose-Einstein condensates which are usually difficult to access.

Peptidomimetics open new opportunities in drug discovery

07/06/2024
A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.

Digital babies created to improve infant healthcare

07/06/2024
Researchers have created digital babies to better understand infants' health in their critical first 180 days of life. The team created 360 advanced computer models that simulate the unique metabolic processes of each baby.

New therapeutic targets to fight type 2 diabetes

07/06/2024
One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production by the liver is triggered, a process that is still full of questions for the scientific community. Now, a review article presents a comprehensive overview of the most important advances in understanding this mechanism.

With programmable pixels, novel sensor improves imaging of neural activity

07/06/2024
New camera chip design allows for optimizing each pixel's timing to maximize signal to noise ratio when tracking real-time visual indicator of neural voltage.

Secure access to food and water decreasing for US children

07/06/2024
The number of children in the U.S. facing simultaneous water and food insecurity more than doubled between 2005 and 2020. Additionally, Black children were 3.5 times more likely than white children to simultaneously experience food and water insecurity, while Hispanic children were 7.1 times more likely than white children, according to a new study.

Engineering cancer's end: Scientists say bioengineering will change our ability to research and treat cancer

07/06/2024
Bioengineering is revolutionizing cancer research. This area of science integrates engineering and physical sciences with oncology to change how we understand and treat this complex disease.

Earth and space share the same turbulence

07/06/2024
Researchers have discovered that the turbulence found in the thermosphere -- known as the gateway to space -- and turbulence in the troposphere, here closer to sea level, follow the same physical laws despite having drastically different atmospheric compositions and dynamics.

Silkworms help grow better organ-like tissues in labs

07/06/2024
Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.

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