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Gene-editing offers hope for people with hereditary disorder

02/02/2024
A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

Edge-to-edge assembly technique for 2D nanosheets

02/02/2024
A research team develops edge-to-edge assembly technique for 2D nanosheets.

Scientists uncover a crucial link between cholesterol synthesis and cancer progression

02/02/2024
A study has found an important connection between cancer, stem cells and the building blocks of cholesterol. Specifically, the research reveals how the enzyme FAXDC2 influences cancer cell growth and differentiation through its role in cholesterol synthesis, suggesting possible new approaches to cancer treatment.

Scammed! Animals 'led by the nose' to leave plants alone

02/02/2024
Fake news works for wallabies and elephants. Herbivores can cause substantial damage to crops or endangered or protected plants, with traditional methods to deter foraging lethal, expensive or ineffective. Biologists are now using aromas from plants naturally repellent with remarkable success to deter the animals.

Epigenetic status determines metastasis

02/02/2024
Scientists nvestigated in mice how spreading tumor cells behave at the site of metastasis: Some tumor cells immediately start to form metastases. Others leave the blood vessel and may then enter a long period of dormancy. What determines which path the cancer cells take is their epigenetic status. This was also confirmed in experiments with human tumor cells. The results of the study could pave the way for novel diagnostic and therapeutic applications.

Prehistoric mobility among Tibetan farmers, herders shaped highland settlement patterns, cultural interaction, study finds

02/02/2024
Using advanced geospatial modeling to compare environmental and archaeological evidence, researchers found evidence that connects ancient mobility and subsistence strategies to cultural connections forged among Tibetan farmers and herders in the Bronze and Iron Ages -- adding to understanding of how and why ancient communities built social relationships and cultural identities across the extreme terrain in Tibet.

Why are people climate change deniers?

02/02/2024
Do climate change deniers bend the facts to avoid having to modify their environmentally harmful behavior? Researchers ran an online experiment involving 4,000 US adults, and found no evidence to support this idea. The authors of the study were themselves surprised by the results. Whether they are good or bad news for the fight against global heating remains to be seen.

Rare 3D fossils show that some early trees had forms unlike any you've ever seen

02/02/2024
In the fossil record, trees typically are preserved with only their trunks. They don't usually include any leaves to show what their canopies and overall forms may have looked like. In a new study, researchers describe fossilized trees from New Brunswick, Canada with a surprising and unique three-dimensional crown shape.

How leafcutter ants cultivate a fungal garden to degrade plants and provide insights into future biofuels

02/02/2024
Scientists developed a new method to map exactly how a fungus works with leafcutter ants in a complex microbial community to degrade plant material at the molecular level. The team's insights are important for biofuels development.

Disrupted cellular function behind type 2 diabetes in obesity

02/02/2024
Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.

A clutch stretch goes a long way

02/02/2024
New results reveal a new mode of force transmission in which dynamic molecular stretching bridges the extracellular matrix and flowing F-actin moving at different speeds. This discovery underscores the necessity of molecular elasticity and random coupling for sufficiently transmitting force. The findings also call for revising the role of molecular unfolding.

Zebrafish navigate to find their comfortable temperature

02/02/2024
Zebrafish are smaller than your little finger, with a brain no more than half the size of a pinhead. Yet these animals possess an efficient navigation system that enables them to find their way back to spots in the water where the temperature suits them.

Researchers use the eye as a window to study liver health

02/02/2024
Researchers have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window into the body to monitor liver health over time.

Researchers 3D-print functional human brain tissue

02/02/2024
It's an achievement with important implications for scientists studying the brain and working on treatments for a broad range of neurological and neurodevelopmental disorders, such as Alzheimer's and Parkinson's disease.

AI learns through the eyes and ears of a child

02/02/2024
Researchers have been skeptical that recent AI advances can tell us much about human learning and development. To address this, a team training an AI model, not on massive data, but on the input that a single child receives. Their findings showed that the model could learn a substantial number of words and concepts using limited slices of what the child experienced.

Clown anemonefish seem to be counting bars and laying down the law

02/02/2024
We often think of fish as carefree swimmers in the ocean, reacting to the world around them without much forethought. However, new research suggests that our marine cousins may be more cognizant than we credit them for. Fish may be counting vertical bars on intruders to determine their threat level, and to inform the social hierarchy governing their sea anemone colonies.

The arrangement of bacteria in biofilms affects their sensitivity to antibiotics

02/02/2024
Many bacteria form an antibiotic-resistant slime. Research detailing that slime's structure could help lead to new treatments.

Human cells building 'molecular highways' captured for first time

02/02/2024
Researchers have captured the world's first high-resolution images of the earliest moments of microtubules forming inside human cells. The findings lay the foundations for potential breakthroughs in treating many different types of diseases ranging from cancer to neurodevelopmental disorders.

Diabetes and liver cancer: Study suggests new screening guidelines

02/02/2024
A new study identifies an easily measured biophysical property that can identify Type 2 diabetics at increased risk for liver cancer who don't meet current screening guidelines.

Psychological care delivered over the phone is an effective way to combat loneliness and depression, according to a major new study

02/02/2024
The results of the study, a major clinical trial carried out during the Covid pandemic, showed rapid and enduring improvements in mental health and quality of life when older people received weekly phone calls over eight weeks from a specially trained coach who encouraged them to maintain their social connections and to remain active.

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