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Promising heart drugs ID'd by cutting-edge combo of machine learning, human learning

01/02/2024
Scientists have developed a new approach to machine learning -- a form of artificial intelligence -- to identify drugs that help minimize harmful scarring after a heart attack or other injuries.

When a stressful situation is perceived as a threat, health and wellbeing suffer

01/02/2024
People experience more health and wellbeing issues when they feel overwhelmed by stressful situations rather than seeing them as a challenge, a new study finds.

Intensifying the production of high-value compounds from industrial waste

01/02/2024
New research demonstrates how glycerol carbonate, a biosourced industrial additive, can be produced in record time using CO2 and a by-product of the cooking oil recycling industry. The process relies on a hybrid approach combining fundamental physical organic chemistry and applied flow process technology. Two industrial wastes are thus converted into glycerol carbonate, a biosourced rising star with high added-value.

Microbial research unravels a global nitrogen mystery

01/02/2024
A research findings show that different AOM lineages employ different regulatory strategies for ammonia or urea utilization, thereby minimizing direct competition with one another and allowing for coexistence.

Shining a new light on the tug-of-war between virus and host

01/02/2024
The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.

Engineers unmask nanoplastics in oceans for the first time, revealing their true shapes and chemistry

01/02/2024
Millions of tons of plastic waste enter the oceans each year. The sun's ultraviolet light and ocean turbulence break down these plastics into invisible nanoparticles that threaten marine ecosystems. In a new study, engineers have presented clear images of nanoplastics in ocean water off the coasts of China, South Korea and the United States, and in the Gulf of Mexico. These tiny plastic particles, which originated from such consumer products as water bottles, food packaging and clothing, were found to have surprising diversity in shape and chemical composition.

Swarming cicadas, stock traders, and the wisdom of the crowd

01/02/2024
The springtime emergence of vast swarms of cicadas can be explained by a mathematical model of collective decision-making with similarities to models describing stock market crashes.

Highly targeted CRISPR delivery system advances gene editing in living animals

01/02/2024
By attaching two kinds of antibody fragments to membrane-derived globules, researchers selectively delivered CRISPR-Cas9, guide RNA and a transgene to T-cells in living mice to create CAR T-cells. While this technique could make it easier to create CAR T-cells in vivo for cancer therapy, the ultimate goal is to selectively target CRISPR-filled 'enveloped delivery vehicles' to any type of cell and avoid the ex vivo cell editing now used in current gene therapies.

Trees struggle to 'breathe' as climate warms

01/02/2024
Trees are struggling to sequester heat-trapping carbon dioxide (CO2) in warmer, drier climates, meaning that they may no longer serve as a solution for offsetting humanity's carbon footprint as the planet continues to warm, according to a new study.

A new way to visualize brain cancer

01/02/2024
Researchers have unveiled unprecedentedly detailed images of brain cancer tissue through the use of a new microscopy technology called decrowding expansion pathology (dExPath).

Climate change threatens older elephants most, jeopardizing African elephants' future

01/02/2024
A collaborative team of researchers has conducted first-of-its kind research into how global climate change affects African elephants. The work shows that older elephants will have markedly decreased chances of survival, which will not only drastically reduce the species' overall ability to weather the changing climate but will send ripple effects throughout the surrounding landscape. The team has also modeled possible mitigation scenarios.

Exposure to even moderate levels of radon linked to increased risk of stroke

01/02/2024
Radon is the second leading cause of lung cancer. Now a new study has found exposure to this invisible, odorless gas is also linked to an increased risk of stroke. The study, which examined exposures in middle age to older female participants, found an increased risk of stroke among those exposed to high and even moderate concentrations of the gas compared to those exposed to the lowest concentrations. The study does not prove that exposure to radon causes stroke; it only shows an association.

Polycystic ovary syndrome tied to memory, thinking problems

01/02/2024
People with polycystic ovary syndrome may be more likely to have memory and thinking problems in middle age, according to new research. The study does not prove that polycystic ovary syndrome causes cognitive decline. It only shows an association.

Diabetes medication class tied to lower risk of kidney stones

01/02/2024
Type 2 diabetes is associated with increased risk of kidney stones, but some forms of treatment for this condition may also have the benefit of lowering risk of kidney stones. Researchers found that there was an association between the use of sodium-glucose contratransporter 2 (SGLT2) inhibitors and a lower risk of developing kidney stones.

Engineers develop hack to make automotive radar 'hallucinate'

01/02/2024
Engineers have demonstrated a system they've dubbed 'MadRadar' for fooling automotive radar sensors into believing almost anything is possible. The technology can hide the approach of an existing car, create a phantom car where none exists or even trick the radar into thinking a real car has quickly deviated from its actual course. And it can achieve this feat in the blink of an eye without having any prior knowledge about the specific settings of the victim's radar, making it the most troublesome threat to radar security to date.

Did dementia exist in ancient Greek and Rome?

01/02/2024
Did the ancient Greeks and Romans experience Alzheimer's? Medical texts from 2,500 years ago rarely mention severe memory loss, suggesting today's widespread dementia stems from modern environments and lifestyles, a new analysis shows.

Scientists make breakthrough in quantum materials research

01/02/2024
Researchers describe the discovery of a new method that transforms everyday materials like glass into materials scientists can use to make quantum computers.

Researchers hack neurons' internal clocks to accelerate the study of neurological diseases

01/02/2024
New research has uncovered a way to 'hack' neurons' internal clocks to speed up their development. The approach promises to accelerate research into neurological disease.

Bright galaxies put dark matter to the test

01/02/2024
The earliest galaxies are thought to have formed as the gravitational pull of dark matter, which has been impossible to study directly, slowly drew in enough hydrogen and helium to ignite stars. But astrophysicists now show that after the Big Bang, hydrogen and helium gas bounced at supersonic speeds off dense, slowly moving clumps of cold dark matter. When the gas fell back in millennia later, stars formed all at once, creating small, exceptionally bright galaxies. If models of cold dark matter are correct, the James Webb Space Telescope should be able to find patches of bright galaxies in the early universe, potentially offering the first effective test for theories about dark matter. If it doesn't, scientists have to go back to the drawing board with dark matter.

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

01/02/2024
Axon damage is an early sign of neurodegenerative diseases like, ALS, Alzheimer's, Huntington's and Parkinson's. Researchers found that nicotinamide nucleotide adenylyl transferase 2, or NMNAT2, can play an important role in keeping axons healthy and functional as people age.

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