Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.
A team has taken the first atomic-resolution images and demonstrated electrical control of a chiral interface state -- an exotic quantum phenomenon that could help researchers advance quantum computing and energy-efficient electronics.
Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings in indicate that periostin, or POSTN, promotes ESCC progression by enhancing cancer and stromal cell migration in cancer-associated fibroblasts (CAFs). Therefore, it may be a novel therapeutic target for treating ESCC.
Researchers use network analysis to study whether it can reveal the subtle changes associated with subjective cognitive decline that cannot otherwise be detected through standard test analyses. By running a statistical analysis of data merged from two large Canadian data sets, the researchers were able to visualize the strength of relationships between the nodes among people who are classified as cognitively normal (CN), or who have diagnoses of subjective cognitive decline (SCD), mild cognitive impairment (MCI) or Alzheimer's disease (AD).
Researchers have identified new variations in neuroblastoma that could lead to a more accurate prognosis and better-targeted treatments for this devastating childhood cancer. A study reveals three new subgroups of the most common type of neuroblastoma, each with different genetic traits, expected outcomes, and distinguishing features that offer clues as to which treatments may be most effective.
An improved charging protocol might help lithium-ion batteries to last much longer. Charging with a high-frequency pulsed current reduces aging effects, an international team demonstrated.
Researchers have discovered a simple, but effective, strategy to help people reduce their feelings of anger. Disposing of a piece of paper containing your written thoughts on the cause of your anger can effectively neutralize it. This process is like a Japanese tradition called hakidashisara, in which people write their negative thoughts on a plate then destroy it. Their findings suggest a simple and effective method of suppressing anger supported by science.
Common 'hard' coastal defenses, like concrete sea walls, might struggle to keep up with increasing climate risks. A new study shows that combining them with nature-based solutions could, in some contexts, create defenses which are better able to adapt.
Byzantine bullion fueled Europe's revolutionary adoption of silver coins in the mid-7th century, only to be overtaken by silver from a mine in Charlemagne's Francia a century later, new tests reveal. The findings could transform our understanding of Europe's economic and political development.
Researchers offer insights into the ethical dilemmas and legal complexities surrounding brain organoids, especially those derived from human fetal tissue. Their findings advocate for thorough regulatory frameworks to ensure that scientific and medical progress in this field is conducted responsibly and ethically, with strong regulations supported by sound ethical and legal principles.
The globe has now experienced 12 months with average monthly temperatures 1.58 degrees Celsius (2.8 degrees Fahrenheit) above the Paris threshold, according to Copernicus data.
The 42.7-metre Angara launch vehicle, capable of carrying payloads bigger than 20 tonnes into orbit, is being developed to replace Russia's Proton M as Russia's heavy-lift rocket
Researchers found an insertion between two pieces of the TBXT gene, which prevented apes from producing a protein required to form a tail
The mosquito bat is a portable thunderstorm for mosquitoes
Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers have found.
Carbon monoxide emissions from industrial production have serious consequences for human health and are a strong indicator of overall air pollution levels. Many countries aim to reduce their emissions, but they cannot control air flows originating in other regions. A new study looks at global flows of air pollution and how they relate to economic activity in the global supply chain.
A study suggests families with infertile male relatives may face elevated cancer risks. Tapping into genetic data, families could help personalize cancer risk assessments.
Scientists discovered that the biological instructions within these vesicles differed significantly in postmortem brain samples donated from patients suffering from Alzheimer's disease.
Eclipse mania gripped all of Mexico, the U.S. and Canada, as the moon swept in front of the sun, blotting out daylight
Researchers have developed a new method to predict the financial impacts climate change will have on agriculture, which can help support food security and financial stability for countries increasingly prone to climate catastrophes.
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