Researchers have found that inhibiting a key protein can stop the destruction of synapses and dendritic spines commonly seen in Alzheimer's disease.
The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these toxic proteins also influences oocyte quality and female fertility. The researchers discovered that mouse oocytes have specialized structures which roam the cytoplasm and act like a clean-up crew which capture and hold onto protein aggregates, rendering them harmless. Failure to degrade the toxic proteins led to the formation of defective eggs. 3 in 5 (60%) of mouse embryos that inherited the toxic proteins failed to complete the very earlies stages of development. The study presents a new frontier to explore the underlying mechanisms of poor oocyte quality, which is the leading cause of female infertility.
A few years ago, astronomers uncovered one of the Milky Way's greatest secrets: an enormous, wave-shaped chain of gaseous clouds in our sun's backyard, giving birth to clusters of stars along the spiral arm of the galaxy we call home. Naming this astonishing new structure the Radcliffe Wave, the team now reports that the Radcliffe Wave not only looks like a wave, but also moves like one -- oscillating through space-time much like 'the wave' moving through a stadium full of fans.
Despite the technological advances keeping meat fresh for as long as possible, certain aging processes are unavoidable. Adenosine triphosphate is a molecule produced by breathing and responsible for providing energy to cells. When an animal stops breathing, ATP synthesis also stops, and the existing molecules decompose into acid, diminishing first flavor and then safety. Hypoxanthine and xanthine are intermediate steps in this transition. Assessing their prevalence in meat indicates its freshness.
By analysing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.
Smiling for just a split second makes people more likely to see happiness in expressionless faces, new research has revealed. The study shows that even a brief weak grin makes faces appear more joyful. The pioneering experiment used electrical stimulation to spark smiles and was inspired by photographs made famous by Charles Darwin.
With GPS data from as little as 6% of vehicles on the road, researchers can recalibrate traffic signals to significantly reduce congestion and delays at intersections.
Researchers reported finding microplastics in all 62 of the placenta samples tested, with concentrations ranging from 6.5 to 790 micrograms per gram of tissue.
Scientists discovered a new target for reversible, non-hormonal male birth control. The drug, an HDAC inhibitor, blocked sperm production and fertility in male mice without affecting libido or future reproduction.
Researchers have found a correlation between early signs of adrenal puberty in first-born daughters and their mothers' having experienced high levels of prenatal stress. They did not find the same result in boys or daughters who were not first-born.
In Nara, Japan, the revered sika deer faces a dilemma as their escalating population damages local farmlands. A new study has revealed a complex situation: while the sanctuary's deer upholds a distinct genetic identity, the surrounding areas display a blend of genetic lineages. This exposes a pressing predicament: whether to cull the 'pest' deer around sanctuary or risk losing a sacred genetic legacy.
Researchers are studying how bats can carry deadly viruses, but not develop symptoms. They found that what happens during swarming behavior -- like social gatherings for bats -- may hold the key to understanding their viral tolerance and translate to human health in fighting off diseases like Ebola and COVID-19.
Scientists have found a black hole surrounded by the largest and brightest disc of captive matter ever discovered.
A new study has revealed a surprising truth about a fossil celebrated for decades as one of the best-preserved fossils from the Alps
Green anacondas are the world’s heaviest snakes, and among the longest
Elon Musk - the owner of SpaceX, the world’s most successful rocket launcher – seized on the failure to prevail over state-owned China Great Wall Industry Corp (CGWIC) as Jakarta’s company of choice for putting satellites into space.
A new study shows there is a gender gap between women and men when it comes to exercise. The findings show that women can exercise less often than men, yet receive greater cardiovascular gains.
Researchers have developed a powerful new artificial intelligence model that can distinguish between male and female brains.
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