Investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings could lead to the development of noninvasive tests to detect kidney scarring and, eventually, new therapies to reverse the condition.
More than 100 million years ago, the ancestors of the first snakes were small lizards that lived alongside other small, nondescript lizards in the shadow of the dinosaurs.
The side effects of large-scale forestation initiatives could reduce the CO2 removal benefits by up to a third, a pioneering study has found.
Nearly 30 years ago, scientists discovered a unique class of anticancer molecules in a family of bryozoans, a phylum of marine invertebrates found in tropical waters. The chemical structures of these molecules, which consist of a dense, highly complex knot of oxidized rings and nitrogen atoms, has attracted the interest of organic chemists worldwide, who aimed to recreate these structures from scratch in the laboratory. However, despite considerable effort, it has remained an elusive task. Until now, that is. A team of chemists has succeeded in synthesizing eight of the compounds for the first time using an approach that combines inventive chemical strategy with the latest technology in small molecule structure determination.
Researchers have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. Bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance genes which are linked to 'jumping genes' that can move from strain to strain. Duplicate genes provide a mechanism for resistance to spread and enable evolving resistance to new drugs.
Forests in the coolest, wettest parts of the western Pacific Northwest are likely to see the biggest increases in burn probability, fire size and number of blazes as the climate continues to get warmer and drier.
NASA's James Webb Space Telescope has found the best evidence yet for emission from a neutron star at the site of a recently observed supernova. The supernova, known as SN 1987A, was a core-collapse supernova, meaning the compacted remains at its core formed either a neutron star or a black hole. Evidence for such a compact object has long been sought, and while indirect evidence for the presence of a neutron star has previously been found, this is the first time that the effects of high-energy emission from the probable young neutron star have been detected.
Remember the 2022 baby formula crisis? The historic shortage of infant formula that year highlighted the precarious balance between regulation, competition and safety, according to a new study. The article takes a close look at the infant formula market and factors that contributed to the crisis.
Nations like South Sudan and Mali, where Guinea worm disease was once more common, have made commendable progress, although the fight continues in Chad and the Central African Republic.
Despite the spotty communication, Intuitive Machines, the private company that built and managed Odysseus, confirmed that the craft had landed
Mice that received fecal implants from donors that had their ovaries removed gained more fat mass and had greater expression of liver genes associated with inflammation, Type 2 diabetes, fatty liver disease and atherosclerosis. The findings may shed light on the greater incidence of metabolic dysfunction in postmenopausal women.
How did cooperative behavior prevail in human evolution? Researchers have challenged two prevailing explanations -- repeated interactions on the one hand or group competition on the other. Instead, both mechanisms synergistically contribute to fostering cooperation effectively.
Luke Skywalker's childhood might have been slightly less harsh if he'd grown up on a more temperate Tatooine -- like the ones identified in a new study. According to the study's authors, there are more climate-friendly planets in binary star systems -- in other words, those with two suns -- than previously known. And, they say, it may be a sign that, at least in some ways, the universe leans in the direction of orderly alignment rather than chaotic misalignment.
Medical summarization, a process that uses artificial intelligence (AI) to condense complex patient information, is currently used in health care settings for tasks such as creating electronic health records and simplifying medical text for insurance claims processing. While the practice is intended to create efficiencies, it can be labor-intensive, according researchers who created a new method to streamline the way AI creates these summaries, efficiently producing more reliable results.
Researchers have unveiled a novel concept termed 'supercritical coupling' that enables several folds increase in photon upconversion efficiency. This discovery not only challenges existing paradigms, but also opens a new direction in the control of light emission.
Scientists have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their research pinpointed a misbehaving protein as a promising therapeutic target in the treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
The annual rate of carbon emissions due to the degradation of carbon stocks in mangrove forests is predicted to rise by nearly 50,000% by the end of the century, according to a new study. Mangroves in regions such as southern India, southeastern China, Singapore and eastern Australia are particularly affected.
In a new study, researchers broke down how human-induced greenhouse gas and aerosol emissions influence rainfall in the United States. Greenhouse gas emissions increase rainfall, while aerosols have a long-term drying effect as well as short-term impacts that vary with the seasons. As aerosols decrease, their long-term drying effect will likely diminish, causing rainfall averages and extremes to rapidly increase.
Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Australia can lay claim to two new species of native rodent thanks to a new study. The aptly named delicate mouse was previously thought to be a single species spanning a massive stretch of the country from the Pilbara in Western Australia, across parts of the Northern Territory and through Queensland down to the New South Wales border. We now know there are three distinct species.
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