A new study shows that analyzing nasal microbiota outperforms gut microbiota analysis to predict sepsis in the ICU.
CAR-T cell therapies are transforming the treatment of previously incurable blood cancers, but a large proportion of patients still responds only poorly or not at all to them, calling for new strategies to overcome this challenge. Now, a research team has developed a simple intervention in the form of a biodegradable scaffold material called 'T-cell enhancing scaffolds' (TES) that can be locally injected under the skin and used to restimulate CAR-T cells after their administration. This increased their therapeutic efficacy and significantly curbed tumor growth and prolonged animal survival in an aggressive mouse lymphoma model.
Scientists have developed an artificial intelligence (AI)-powered system to track tiny devices that monitor markers of disease in the gut. Devices using the novel system may help at-risk individuals monitor their gastrointestinal (GI) tract health at home, without the need for invasive tests in hospital settings.
A mother's contribution to the makeup of a newborn baby's microbiota has been well documented. Now a new article shows the important contributions that fathers make to the composition of microorganisms colonizing a baby's gut as well. Furthermore, the study confirmed that maternal fecal microbiota transfer (FMT) in babies born by caesarean section can help to correct the microbiota disturbances often observed in babies who are not born vaginally.
Researchers have demonstrated a new method that leverages artificial intelligence (AI) and computer simulations to train robotic exoskeletons to autonomously help users save energy while walking, running and climbing stairs.
Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer. Now, a new study introduces an original technique, called HiDEF-seq, that can accurately detect the early molecular changes in DNA code that precede mutations.
Researchers have reconstructed the evolutionary history and global spread of malaria over the past 5,500 years, identifying trade, warfare, and colonialism as major catalysts for its dispersal.
Rising to power in the wake of the Classic Maya collapse, Chich n Itz was among the largest and most influential cities of the ancient Maya, but much about its political connections and ritual life remain poorly understood. Close kin relationships, including two pairs of identical twins, suggests a connection to the Maya origin myths of the Popol Vuh. Further comparison to Maya populations today reveals the genetic impact of colonial-era epidemics.
Researchers found that mental representations known as cognitive maps, located in the hippocampus and entorhinal cortex, are activated when the brain performs mental simulations of a navigational route.
Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer. The findings provide a mechanistic explanation for how obesity can contribute to both increased cancer risk and enhanced responses to immunotherapy.
New research adds to growing evidence that widely used and user-friendly consumer devices, in this instance an Apple Watch paired with an iPhone, can detect changes in Parkinson's symptoms over time in individuals in the early stages of the disease.
In the largest study yet of working-from-home professionals, economists reveal that employees who work from home two days a week are just as productive, likely to get promoted, and far less prone to quit.
Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX. These genetic variants may play a role in promoting abnormal blood cells (that have only a single copy of chromosome X) to multiply, which may lead to several health conditions, including cancer.
A new study conducted on fruit flies reports the first evidence that oocytes -- the cells that become eggs -- regularly rejuvenate the critical protein linkages that bind chromosomes together. The findings are a potentially important step toward helping women reduce their risk of pregnancy complications as they age.
The Government of Andhra Pradesh, Department of School Education, is set to release the AP TET Results 2024 soon on aptet.apcfss.in. Conducted from February 27 to March 9, the exam's results were delayed due to the Lok Sabha Elections 2024. Candidates can check their results by entering their registration number and date of birth on the official website. The provisional and final answer keys were released on March 4 and March 14, respectively.
The SSC has released the application status for all SSC Selection Phase 12 regions. Candidates can now view their application details on the official website. While admit cards aren't available yet, the SSC is preparing to release them in phases for all regions. The exams are scheduled for June 20-26. Stay updated on the official SSC website (including regional websites) for admit card release announcements. The admit card contains exam details and is mandatory for the exam hall along with a valid ID.
The National Testing Agency (NTA) has faced intense scrutiny over allegations of irregularities in the NEET-UG 2024 exam, including paper leaks and scoring anomalies. In response, the NTA released a comprehensive set of FAQs to address concerns, explaining the role of the Grievance Redressal Committee, the calculation of compensatory marks, and the reasons behind the unprecedented number of perfect scores.
On the recommendation of the PRL, the International Astronomical Union (IAU) Working Group for Planetary System Nomenclature approved naming the three craters on Mars.
The Chhattisgarh Professional Examination Board (CGPEB) in Raipur is closing the application correction window for the Chhattisgarh State Eligibility Test (CG SET) 2024 today, June 12. Registered candidates can make necessary changes to their CG SET 2024 application forms on the official website, vyapam.cgstate.gov.in, before the deadline. The CG SET 2024 exam is scheduled for July 21 with two sessions at various exam centers across the state. Paper 1 will take place from 10 am to 11:15 am, and Paper 2 from 2 pm to 4:15 pm.
The Bank of Baroda has announced the recruitment of 627 positions in 2024, including 459 contract positions and 168 regular positions in the Corporate & Institutional Credit and Finance Department. Applications open from 12 June 2024 to 2 July 2024 on the official website. The selection process includes a written exam or interview, document verification, and a medical examination.
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