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Revealing the evolutionary origin of genomic imprinting

07/03/2024
Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father. The mechanism behind this phenomenon, known as genomic imprinting, is determined by DNA modifications during egg and sperm production.

Universal tool for tracking cell-to-cell interactions

07/03/2024
An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.

Synthetic gene helps explain the mysteries of transcription across species

07/03/2024
'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.

Compact chips advance precision timing for communications, navigation and other applications

07/03/2024
Precision timing and synchronization are crucial for navigation, communication and radar systems. Scientists have built compact chips capable of converting light into microwaves, which could improve these systems. This technology shrinks a tabletop system into a chip-sized format, reducing power usage and making it more applicable for use in everyday devices.

Decoding the language of epigenetic modifications

07/03/2024
Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.

New microscopy tech answers fundamental questions

07/03/2024
A new tool captures data from an unprecedented 1 million neurons simultaneously, painting a much fuller picture of brain dynamics.

Deconstructing the structural elements of a lesser-known microbe

07/03/2024
Researchers shed light on archaea, intriguing microbes found in extreme environments but also in the human gut microbiome.

Psychosocial stressors linked to higher inflammation in Black pregnant women

07/03/2024
Living in neighborhoods with more white residents and greater lifetime experiences of racial discrimination are linked to increased systemic inflammation during pregnancy among Black women, according to new research.

Amyloid blood levels associated with brain changes in Alzheimer's study

07/03/2024
A link between abnormal blood levels of amyloid -- a protein associated with Alzheimer's disease -- and subtle changes in brain microstructures on a type of MRI could lead to a new way to detect Alzheimer's earlier in people with no clinical signs.

Study reveals genetic clusters and biological pathways that may explain differences in type 2 diabetes risk

07/03/2024
A recent study analyzed individuals from diverse backgrounds and identified various genetic clusters involved in a broad range of biological mechanisms that may help explain ancestry-associated differences in type 2 diabetes clinical presentations.

Herbivores, displaced by ocean warming, threaten subtropical seagrass meadows

07/03/2024
The findings suggest that subtropical seagrasses are less resilient to heavy grazing from marine herbivores, in part because they receive less sunlight relative to their tropical counterparts. As tropical herbivores move into subtropical waters, overgrazing may prevent subtropical seagrass meadows from persisting in these environments.

A step towards clinic-ready patient-derived organoids

07/03/2024
A recent study provides critical insights into the reliability and robustness of patient-derived organoids as a clinical model of pancreatic cancer. The findings reveal that organoids' gene expression and drug responses are not affected by the brand of extracellular matrix used in the cell culture. However, one commercial product did increase the growth rate of pancreatic tumor organoids, making it particularly well-suited for the fast pace of pancreatic cancer treatment protocols.

Discovery tests theory on cooling of white dwarf stars

07/03/2024
Open any astronomy textbook to the section on white dwarf stars and you'll likely learn that they are 'dead stars' that continuously cool down over time. Astronomers are challenging this theory after discovering a population of white dwarf stars that stopped cooling for more than eight billion years.

Invasive plant time bombs: A hidden ecological threat

07/03/2024
Invasive plants can stay dormant for decades or even centuries before rapidly expanding and wreaking ecological havoc, finds a new study.

Older adults want to express themselves with emojis, they just don't understand how to

07/03/2024
A new study is providing insight into how different generations are interpreting the use of emojis in their communications, with older adults unsure of how to use them as frequently as younger adults despite understanding their meaning.

Consuming refined carbs might be linked to perceived facial attractiveness

07/03/2024
In a new study, participants' levels of consumption of refined carbohydrates were statistically linked with their facial attractiveness as rated by heterosexual volunteers of the opposite sex.

COVID-19 physiological impacts vary by sex, wearable technology reveals

07/03/2024
Males and females have differential physiological responses to COVID-19 infections, with males having larger increases in skin temperature, breathing rate and heart rate during an acute infection, according to a new study that used data from wearable devices.

Factors associated with age-related hearing loss differ between males and females

07/03/2024
Certain factors associated with developing age-related hearing loss differ by sex, including weight, smoking behavior, and hormone exposure, according to a new study.

This injectable hydrogel mitigates damage to the right ventricle of the heart

07/03/2024
An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study. In 2019, this same hydrogel was shown to be safe in humans through an FDA-approved Phase 1 trial in people who suffered a heart attack. As a result of the new preclinical study, the FDA approved an investigational new drug application to start a clinical trial with the hydrogel in pediatric patients in the coming months, once institutional approvals are received.

New deep-sea worm discovered at methane seep off Costa Rica

07/03/2024
Marine biologists have discovered a new species of deep-sea worm living near a methane seep some 50 kilometers (30 miles) off the Pacific coast of Costa Rica.

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