Science Daily

A specific protein, TP53INP2, might prevent muscle loss associated with aging. A new study indicates that high levels of this protein are linked to greater muscle strength and healthier aging. This discovery paves the way for new treatments that could enhance the quality of life for the elderly.

Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal. Researchers have recently developed a deep-learning model capable of predicting the transition from a normal cardiac rhythm to atrial fibrillation. It gives early warnings on average 30 minutes before onset, with an accuracy of around 80%. These results pave the way for integration into wearable technologies, allowing early interventions and better patient outcomes.

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study.

The study highlights the rapid progress and transformative potential of AI in weather prediction.

Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.

Magnetic two-dimensional materials consisting of one or a few atomic layers have only recently become known and promise interesting applications, for example for the electronics of the future. So far, however, it has not been possible to control the magnetic states of these materials well enough. A research team is now presenting an innovative idea that could overcome this shortcoming -- by allowing the 2D layer to react with hydrogen.

Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.

Lithium salts make batteries powerful but expensive. An ultralow-concentration electrolyte based on the lithium salt LiDFOB may be a more economical and more sustainable alternative. Cells using these electrolytes and conventional electrodes have been demonstrated to have high performance. In addition, the electrolyte could facilitate both production and recycling of the batteries.

Simulated effects of microgravity significantly affect rhythmicity and sleep in humans, a new study finds. Such disturbances could negatively affect the physiology and performance of astronauts in space.

Scientists are developing and validating a patent-pending novel immunotherapy to be used against glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 months. Traditional methods used against other cancers, like chemotherapy and immunotherapy, are often ineffective on glioblastoma.

Superradiant atoms can help us measure time more precisely than ever. In a new study, researchers present a new method for measuring the time interval, the second, mitigating some of the limitations that today's most advanced atomic clocks encounter. The result could have broad implications in areas such as space travel, volcanic eruptions and GPS systems.

Middle-aged and older adults believe that old age begins later in life than their peers did decades ago, according to a new study.

Researchers who study Earth's biosphere tend to operate from one of three scientific cultures, each with distinct ways of conducting science, and which have been operating mostly independently from one another. The authors identify and explain the three cultures, and suggest that reconnecting them could help accelerate biosphere science.

State-of-the-art artificial intelligence systems known as large language models (LLMs) are poor medical coders, according to researchers. Their study emphasizes the necessity for refinement and validation of these technologies before considering clinical implementation. The study extracted a list of more than 27,000 unique diagnosis and procedure codes from 12 months of routine care in the Mount Sinai Health System, while excluding identifiable patient data. Using the description for each code, the researchers prompted models from OpenAI, Google, and Meta to output the most accurate medical codes. The generated codes were compared with the original codes and errors were analyzed for any patterns.

Clarifying the cause of a skin disease led to the discovery of a new disease-causing gene, a new category of diseases, and new perspectives for both counseling and therapy. The discovery is the first time that epigenetic silencing, the 'switching off' of an otherwise intact gene, has been recognized as the cause for a skin disease.

Primary health care, conditional cash transfers and social pensions have prevented 1.4 million deaths of all ages in Brazil over the past two decades, according to a new study. If expanded, these programs could avert an additional 1.3 million deaths and 6.6 million hospitalizations by 2030.

Based on radio telescope data and models of black hole physics, a team has used neural networks to reconstruct a 3D image that shows how explosive flare-ups in the disk of gas around our supermassive black hole might look.

Anticipating changes to ecosystems is often at best an educated guess, but what if there was a way to better tune into possible changes occurring? Researchers have discovered that the silent growth of non-native invasive plants can affect the soundscape of an ecosystem. These altered soundscapes, the acoustic patterns of a landscape through space and time, may provide a key to better observing the hard-to-see physical and biological changes occurring in an ecosystem as they are beginning.

Inspired by what human liver enzymes can do, chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions are expected to be widely used in drug discovery and optimization, as well as in other chemistry-based industries.

Scientists have gained insights into the weak nuclear force from new, more sensitive studies of the beta decays of the 'mirror' nuclei lithium-8 and boron-8. The weak nuclear force drives the process of nuclear beta decay. The research found that the properties of the beta decays of lithium-8 and boron-8 are in perfect agreement with the predictions of the Standard Model.